Bivalent Omicron BA.1 vaccine booster increases memory B cell breadth and neutralising antibodies against emerging SARS-CoV-2 variantsResearch in context

Summary: Background: Current literature informs us that bivalent vaccines will generate a broader serum neutralizing antibody response to multiple SARS-CoV-2 variants, but studies on how this breadth relates to the memory B cell (MBC) and T cell responses are sparse. This study compared breadth of...

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Hlavní autoři:	Lok Bahadur Shrestha, Katie Tungatt, Anupriya Aggarwal, Aija Stubis, Nicole L. Fewings, Christina Fichter, Anouschka Akerman, Chaturaka Rodrigo, Nicodemus Tedla, Sharon Lee, Andrew R. Lloyd, Fabienne Brilot, Warwick J. Britton, Anthony Kelleher, Ian D. Caterson, Mark W. Douglas, Rebecca Rockett, Stuart G. Tangye, James A. Triccas, Stuart G. Turville, Kerrie J. Sandgren, Rowena A. Bull, Anthony L. Cunningham, Tania Sorrell, Warwick Britton, Mark Maclean, Joanne Camilleri, Mark Douglas, Rowena Bull, Kerrie Sandgren, Yang Song, Lijun Mao, Amy Phu, Allison Sigmund, Sophie Beard, Ian Caterson, Stephanie Hunt, Anne Marie Vande More, Rama Kandasamy, Jen Kok, Jennifer Byrne, Andrew Lloyd, James Triccas, Stuart Tangye, Stuart Turville, Matthew O’Sullivan, Megan Steain, Sarah Baird, Chansavath Phetsouphanh, Yanran Zhao
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2024-12-01
Edice:	EBioMedicine
Témata:	Bivalent vaccine Omicron BA.1 Receptor binding domain Memory B cells JN.1
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2352396424004973
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