Sulforaphane epigenetically regulates innate immune responses of porcine monocyte-derived dendritic cells induced with lipopolysaccharide.

Histone acetylation, regulated by histone deacetylases (HDACs) is a key epigenetic mechanism controlling gene expressions. Although dendritic cells (DCs) are playing pivotal roles in host immune responses, the effect of epigenetic modulation of DCs immune responses remains unknown. Sulforaphane (SFN...

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Detalhes bibliográficos

Principais autores:	Xueqi Qu, Maren Pröll, Christiane Neuhoff, Rui Zhang, Mehmet Ulas Cinar, Md Munir Hossain, Dawit Tesfaye, Christine Große-Brinkhaus, Dessie Salilew-Wondim, Ernst Tholen, Christian Looft, Michael Hölker, Karl Schellander, Muhammad Jasim Uddin
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2015-01-01
coleção:	PLoS ONE
Acesso em linha:	https://doi.org/10.1371/journal.pone.0121574
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