Systematic assessment of secondary bile acid metabolism in gut microbes reveals distinct metabolic capabilities in inflammatory bowel disease

Abstract Background The human gut microbiome performs important functions in human health and disease. A classic example for host-gut microbial co-metabolism is host biosynthesis of primary bile acids and their subsequent deconjugation and transformation by the gut microbiome. To understand these sy...

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Bibliografiske detaljer

Principais autores:	Almut Heinken, Dmitry A. Ravcheev, Federico Baldini, Laurent Heirendt, Ronan M. T. Fleming, Ines Thiele
Format:	Artigo
Sprog:	Inglês
Udgivet:	BMC 2019-05-01
Serier:	Microbiome
Fag:	Gut microbiome Bile acids Host-microbe interactions Metabolism Genome-scale reconstruction Constraint-based modeling
Online adgang:	http://link.springer.com/article/10.1186/s40168-019-0689-3
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