Design, Synthesis, in vitro biological evaluation and in silico molecular docking study of chloro substituted Benzimidazole-Thiazole hybrid derivatives as potential Anti-Alzheimer’s agents

In order to explore new acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) inhibitors, a series of benzimidazole-fused-thiazole bearing Schiff base derivatives (1–16) were designed and synthesized and further their precise structures were elucidated using various spectroscopic tools inclu...

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Detalhes bibliográficos

Principais autores:	Sana Kaleem, Hayat Ullah, Muhammad Nabi, Rafaqat Hussain, Shoaib Khan, Muhammad Sajid, Naveed Iqbal, Fazal Rahim, Tayyiaba Iqbal, Amjad Hussain, Rashid Iqbal, Zunaira Zahid, Mohamed Mohany, Saltanat Aghayeva
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-06-01
coleção:	Results in Chemistry
Assuntos:	Benzimidazole Thiazole Bis-Schiff Base Acetylcholinesterase Butyrylcholinesterase Molecular docking
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2211715624002996
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