Gli2 and Gli3 synergistically mediate HH-TGF-β crosstalk in mesenchymal progenitor cells to orchestrate tooth root morphogenesis

Abstract Hedgehog (HH) signaling is essential in directing the fate determination of postmigratory cranial neural crest cells (CNCCs) to ensure proper craniofacial development. Gli transcription factors (TFs) are established as primary effectors of HH signaling, yet their distinct roles and regulato...

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Detalles Bibliográficos

Principais autores:	Tao Zhou, Linyang Huang, Yaxin Xie, Yijia Yin, Yufei Yao, Li Mei, Paul R. Cooper, Hu Zhao, Xianglong Han, Junjun Jing
Formato:	Artigo
Idioma:	Inglês
Publicado:	Nature Publishing Group 2026-03-01
Series:	International Journal of Oral Science
Acceso en liña:	https://doi.org/10.1038/s41368-026-00427-6
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