Pseudorabies virus-induced expression and antiviral activity of type I or type III interferon depend on the type of infected epithelial cell

Type I and III Interferons (IFNs) are the initial antiviral cytokines produced in response to virus infection. These IFNs in turn bind to their respective receptors, trigger JAK-STAT signaling and induce the expression of IFN-stimulated genes (ISGs) to engage antiviral functions. Unlike the receptor...

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Bibliografische Detailangaben

Hauptverfasser:	Yue Yin, Jinglin Ma, Cliff Van Waesberghe, Bert Devriendt, Herman W. Favoreel
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2022-11-01
Schriftenreihe:	Frontiers in Immunology
Schlagworte:	epithelial cell pseudorabies virus alphaherpesvirus type I interferon type III interferon respiratory
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.1016982/full
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