Targeted expansion of cytotoxic T cells using IL-12 and CD137L supplementation enhances antitumor efficacy

The increasing success of allogenic Vδ2 T cell immunotherapy for the treatment of cancer has been demonstrated in recent studies. Vδ2 T cells recognize phosphoantigens, intermediates of the mevalonate pathway, through butyrophilin molecules, and they are not major histocompatibility complex (MHC) re...

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Bibliografski detalji

Glavni autori:	Marta Sanz, Brendan T. Mann, Elyse K. McMahon, Alberto Bosque, Samuel Simmens, Natalia Soriano-Sarabia
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2025-06-01
Serija:	Molecular Therapy: Oncology
Teme:	MT: Regular Issue gamma delta T cells Vd2 cells expansion cell therapy alendronate
Online pristup:	http://www.sciencedirect.com/science/article/pii/S2950329925000657
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