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Prion protein alters viral control and enhances pathology after perinatal cytomegalovirus infection

Abstract Cytomegalovirus (CMV) infection poses risks to newborns, necessitating effective therapies. Given that the damage includes both viral infection of brain cells and immune system-related damage, here we investigate the involvement of cellular prion protein (PrP), which plays vital roles in ne...

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Autori principali: Dubravka Karner, Daria Kvestak, Paola Kucan Brlic, Maja Cokaric Brdovcak, Berislav Lisnic, Ilija Brizic, Vanda Juranic Lisnic, Mijo Golemac, Jelena Tomac, Astrid Krmpotic, Esma Karkeni, Valentina Libri, Sebastien Mella, Giuseppe Legname, Hermann C. Altmeppen, Milena Hasan, Stipan Jonjic, Tihana Lenac Rovis
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2024-09-01
Serie:Nature Communications
Accesso online:https://doi.org/10.1038/s41467-024-51931-4
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