Deficiency of malate-aspartate shuttle component SLC25A12 induces pulmonary metastasis
Abstract Background Aspartate biosynthesis and its delivery to the cytosol can be crucial for tumor growth in vivo. However, the impact of intracellular aspartate levels on metastasis has not been studied. We previously described that loss-of-aspartate glutamate carrier 1 (SLC25A12 or AGC1), an impo...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BMC
2020-11-01
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| Серии: | Cancer & Metabolism |
| Предметы: | |
| Online-ссылка: | http://link.springer.com/article/10.1186/s40170-020-00232-7 |
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