Age-dependent impact of streptozotocin on metabolic endpoints and Alzheimer's disease pathologies in 3xTg-AD mice

Alzheimer's disease (AD) is a multifactorial neurodegenerative disease with a complex origin, thought to involve a combination of genetic, biological and environmental factors. Insulin dysfunction has emerged as a potential factor contributing to AD pathogenesis, particularly in individuals with dia...

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Detalhes bibliográficos

Principais autores:	Geoffrey Canet, Maud Gratuze, Charleine Zussy, Mohamed Lala Bouali, Sofia Diego Diaz, Emma Rocaboy, Francis Laliberté, Noura B. El Khoury, Cyntia Tremblay, Françoise Morin, Frédéric Calon, Sébastien S. Hébert, Carl Julien, Emmanuel Planel
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-08-01
coleção:	Neurobiology of Disease
Assuntos:	Alzheimer's disease Insulin deficiency Diabetes mellitus Streptozotocin Tau phosphorylation Amyloid-β
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S0969996124001256
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