Calcium Dobesilate Reverses Cognitive Deficits and Anxiety-Like Behaviors in the D-Galactose-Induced Aging Mouse Model through Modulation of Oxidative Stress

The long-term treatment of mice with D-galactose (D-gal) induces the overproduction of reactive oxygen species (ROS) and is a well-accepted experimental model of oxidative stress-linked cognitive disorders in physiological aging. Calcium dobesilate (CaD, Doxium^®) is an established vasoact...

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Автори:	Elham Hakimizadeh, Mohammad Zamanian, Lydia Giménez-Llort, Clara Sciorati, Marjan Nikbakhtzadeh, Małgorzata Kujawska, Ayat Kaeidi, Jalal Hassanshahi, Iman Fatemi
Формат:	Artigo
Мова:	Inglês
Опубліковано:	MDPI AG 2021-04-01
Серія:	Antioxidants
Предмети:	aging antioxidant activity calcium dobesilate Doxium D-galactose mice
Онлайн доступ:	https://www.mdpi.com/2076-3921/10/5/649
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