Genetic evaluation of relationship between mutations in <it>rpoB </it>and resistance of <it>Mycobacterium tuberculosis </it>to rifampin
<p>Abstract</p> <p>Background</p> <p>Rifampin is a first line antituberculosis drug active against bacilli in logarithmic and stationary phase, which interferes with RNA synthesis by binding to bacterial RNA polymerase. Tubercle bacilli achieve resistance to rifampin by accumulation of mutations in...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
BMC
2009-01-01
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| Σειρά: | BMC Microbiology |
| Διαθέσιμο Online: | http://www.biomedcentral.com/1471-2180/9/10 |
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