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Human biodistribution and dosimetry of [11C]-UCB-J, a PET radiotracer for imaging synaptic density

Abstract Rationale [11C]-UCB-J is an emerging tool for the noninvasive measurement of synaptic vesicle density in vivo. Here, we report human biodistribution and dosimetry estimates derived from sequential whole-body PET using two versions of the OLINDA dosimetry program. Methods Sequential whole-bo...

Whakaahuatanga katoa

I tiakina i:
Ngā kaituhi matua: Christopher Cawthorne, Paul Maguire, Joel Mercier, David Sciberras, Kim Serdons, Guy Bormans, Jan de Hoon, Koen Van Laere, Michel Koole
Hōputu: Artigo
Reo:Inglês
I whakaputaina: SpringerOpen 2021-04-01
Rangatū:EJNMMI Physics
Ngā marau:
[11C]-UCB-J
Synaptic density
Radiation dosimetry
Human biodistribution
OLINDA
Urunga tuihono:https://doi.org/10.1186/s40658-021-00384-5
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