Pharmacological induction of MHC-I expression in tumor cells revitalizes T cell antitumor immunity
Antigen presentation by major histocompatibility complex class I (MHC-I) is crucial for T cell–mediated killing, and aberrant surface MHC-I expression is tightly associated with immune evasion. To address MHC-I downregulation, we conducted a high-throughput flow cytometry screen, identifying bleomyc...
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| Główni autorzy: | , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Clinical investigation
2024-09-01
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| Seria: | JCI Insight |
| Hasła przedmiotowe: | |
| Dostęp online: | https://doi.org/10.1172/jci.insight.177788 |
| Etykiety: |
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