The Key Role of GSH in Keeping the Redox Balance in Mammalian Cells: Mechanisms and Significance of GSH in Detoxification via Formation of Conjugates

Glutathione (GSH) is a ubiquitous tripeptide that is biosynthesized in situ at high concentrations (1–5 mM) and involved in the regulation of cellular homeostasis via multiple mechanisms. The main known action of GSH is its antioxidant capacity, which aids in maintaining the redox cycle of cells. To...

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Bibliografische Detailangaben

Hauptverfasser:	Sofia K. Georgiou-Siafis, Asterios S. Tsiftsoglou
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2023-11-01
Schriftenreihe:	Antioxidants
Schlagworte:	GSH redox cycle GSH S-conjugates GSH adducts GSH metabolism xenobiotics metabolic signatures
Online-Zugang:	https://www.mdpi.com/2076-3921/12/11/1953
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