Nontargeted metabolomics uncovering metabolite signatures in glioblastoma: a preliminary study on candidate biomarker discovery for IDH subtyping and survival prediction

BackgroundCurrently, there are no established tumor-derived metabolic biomarkers in clinical practice that can simultaneously differentiate among nontumorous brain tissues, isocitrate dehydrogenase (IDH) wild-type glioblastomas (GBMs), and IDH mutant GBMs, or accurately predict patient survival. The...

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Bibliografische Detailangaben

Hauptverfasser:	Peng Xu, Xiling Chen, Qun Li, Zheqing Dong, Ji Zhu, Zhipeng Su, Qifan Zhang, Kui Fang
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2025-05-01
Schriftenreihe:	Frontiers in Oncology
Schlagworte:	glioblastoma isocitrate dehydrogenase molecular classification biomarkers survival risk prediction
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fonc.2025.1568040/full
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