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Rho-dependent transcription termination in bacteria recycles RNA polymerases stalled at DNA lesions

In bacteria, the Rho protein dislodges elongation complexes to terminate transcription, and the Mfd protein removes RNA polymerases (RNAPs) stalled at DNA lesions. Here, Jain et al. show that Rho also dissociates stalled RNAPs at DNA lesions, which may facilitate DNA repair and other DNA-dependent p...

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Bibliografiske detaljer
Principais autores: Sriyans Jain, Richa Gupta, Ranjan Sen
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2019-03-01
Serier:Nature Communications
Online adgang:https://doi.org/10.1038/s41467-019-09146-5
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