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Safety Profile of Rapamycin Perfluorocarbon Nanoparticles for Preventing Cisplatin-Induced Kidney Injury

Cancer treatment-induced toxicities may restrict maximal effective dosing for treatment and cancer survivors’ quality of life. It is critical to develop novel strategies that mitigate treatment-induced toxicity without affecting the efficacy of anti-cancer therapies. Rapamycin is a macrolide with an...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Qingyu Zhou, Justin Doherty, Antonina Akk, Luke E. Springer, Ping Fan, Ivan Spasojevic, Ganesh V. Halade, Huanghe Yang, Christine T. N. Pham, Samuel A. Wickline, Hua Pan
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2022-01-01
Schriftenreihe:Nanomaterials
Schlagworte:
rapamycin
perfluorocarbon nanoparticle
autophagy
inflammation
pharmacokinetics
biodistribution
Online-Zugang:https://www.mdpi.com/2079-4991/12/3/336
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