A chromatin-based signalling mechanism directs the switch from mutagenic to error-free repair of DNA double strand breaks
Mutations caused by DNA damage are a main driver of cancer. We discovered that recognition of newly synthesised histone H4 directs breast cancer type 1 susceptibility protein (BRCA1) to post-replicative chromatin. The switch from mutagenic to error-free DNA double strand break repair by homologous r...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis Group
2019-07-01
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| Serie: | Molecular & Cellular Oncology |
| Soggetti: | |
| Accesso online: | http://dx.doi.org/10.1080/23723556.2019.1605820 |
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