Inflammation-driven periostin in ECRS has contrasting effects on tissue structural integrity and osteitis

IntroductionEosinophilic chronic rhinosinusitis (ECRS) is a severe form of chronic rhinosinusitis characterized by type 2 inflammation, tissue remodeling, and bone thickening, known as osteitis. Periostin, a matricellular protein involved in extracellular matrix (ECM) regulation and T helper 2 (Th2)...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Soo-In Kim, Min-Seok Rha, Jinsun Kim, Sang Hyeon Ahn, Ji-Hwan Ryu, Hyung-Ju Cho, Chang-Hoon Kim
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2025-06-01
Schriftenreihe:	Frontiers in Immunology
Schlagworte:	periostin Th2 inflammation eosinophilic chronic rhinosinusitis osteitis tissue remodeling
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1596746/full
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!