Curcumin-like diarylpentanoid analogues exhibit antiviral and anti-inflammatory activities in influenza A virus-infected A549 lung epithelial cells by inhibiting multiple retinoic acid-inducible gene I (RIG-I)-mediated pathways

Abstract Influenza A virus (IAV) causes seasonal epidemics and occasionally pandemics. Curcumin, a well-known phytochemical, has been reported to exhibit anti-IAV effects; however, most studies were not comprehensive and utilized Mardin-Darby canine kidney (MDCK) cells. Curcumin-like diarylpentanoid...

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Main Authors:	Kong Yen Liew, Hui-Yee Chee, Faridah Abas, Sze Wei Leong, Hanis Hazeera Harith, Ming-Tatt Lee, Mohd Roslan Sulaiman, Chau Ling Tham
Format:	Artigo
Language:	Inglês
Published:	BMC 2025-10-01
Series:	Virology Journal
Subjects:	Influenza A virus H1N1 Curcumin Diarylpentanoid analogue Antiviral Cytokine
Online Access:	https://doi.org/10.1186/s12985-025-02914-4
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