Blocking the Trigger: Inhibition of the Initiation of Bacterial Chromosome Replication as an Antimicrobial Strategy

All bacterial cells must duplicate their genomes prior to dividing into two identical daughter cells. Chromosome replication is triggered when a nucleoprotein complex, termed the orisome, assembles, unwinds the duplex DNA, and recruits the proteins required to establish new replication forks. Obviou...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Julia E. Grimwade, Alan C. Leonard
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	MDPI AG 2019-08-01
Цуврал:	Antibiotics
Нөхцлүүд:	antibiotic targets orisome <i>oriC</i> DnaA DnaB DnaC initiation of bacterial DNA replication
Онлайн хандалт:	https://www.mdpi.com/2079-6382/8/3/111
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!