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Navigating structure-based drug discovery with emerging innovations in physics- and knowledge-based approaches

Abstract Structure-based drug design is rapidly evolving, driven by advances in both physics-based and knowledge-based methods. These computational approaches are increasingly integrated across all stages of drug discovery. Despite remarkable progress, challenges remain in achieving accuracy, genera...

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Príomhchruthaitheoirí: Jordy Homing Lam, Vsevolod Katritch
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Nature Portfolio 2025-12-01
Sraith:npj Drug Discovery
Rochtain ar líne:https://doi.org/10.1038/s44386-025-00031-4
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