A Key Role for the Ubiquitin Ligase UBR4 in Myofiber Hypertrophy in Drosophila and Mice

Summary: Skeletal muscle cell (myofiber) atrophy is a detrimental component of aging and cancer that primarily results from muscle protein degradation via the proteasome and ubiquitin ligases. Transcriptional upregulation of some ubiquitin ligases contributes to myofiber atrophy, but little is known...

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Detalhes bibliográficos

Principais autores:	Liam C. Hunt, Jared Stover, Benard Haugen, Timothy I. Shaw, Yuxin Li, Vishwajeeth R. Pagala, David Finkelstein, Elisabeth R. Barton, Yiping Fan, Myriam Labelle, Junmin Peng, Fabio Demontis
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2019-07-01
Colecção:	Cell Reports
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2211124719308800
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