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Tumor RAS Gene Expression Levels Are Influenced by the Mutational Status of RAS Genes and Both Upstream and Downstream RAS Pathway Genes

The 3 human RAS genes play pivotal roles regulating proliferation, differentiation, and survival in normal cells and become mutated in 15% to 20% of all human tumors and amplified in many others. In this report, we examined data from The Cancer Genome Atlas to investigate the relationship between RA...

Ausführliche Beschreibung

Gespeichert in:
Bibliografische Detailangaben
Hauptverfasser: Robert M Stephens, Ming Yi, Bailey Kessing, Dwight V Nissley, Frank McCormick
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publishing 2017-06-01
Schriftenreihe:Cancer Informatics
Online-Zugang:https://doi.org/10.1177/1176935117711944
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