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Glucagon-Like Peptide-1 Receptor Regulates Macrophage Migration in Monosodium Urate-Induced Peritoneal Inflammation

Glucagon-like peptide-1 (GLP-1) is an insulinotropic peptide that signals through the GLP-1 receptor (GLP-1R). GLP-1R, therefore, plays a critical role in diabetes and cardiovascular disease. Whether GLP-1R is involved in inflammatory disease such as gout remains unclear. Macrophages are critical ef...

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Principais autores: Jun Chen, Aihua Mei, Xinxin Liu, Zachary Braunstein, Yingying Wei, Biao Wang, Lihua Duan, Xiaoquan Rao, Sanjay Rajagopalan, Lingli Dong, Jixin Zhong
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2022-01-01
Serier:Frontiers in Immunology
Fag:
gout
GLP-1, glucagon-like peptide-1
macrophage
monosodium urate
inflammation
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2022.772446/full
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