Pivoting between calmodulin lobes triggered by calcium in the Kv7.2/calmodulin complex.
Kv7.2 (KCNQ2) is the principal molecular component of the slow voltage gated M-channel, which strongly influences neuronal excitability. Calmodulin (CaM) binds to two intracellular C-terminal segments of Kv7.2 channels, helices A and B, and it is required for exit from the endoplasmic reticulum. How...
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| Principais autores: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science (PLoS)
2014-01-01
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| coleção: | PLoS ONE |
| Acesso em linha: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24489773/pdf/?tool=EBI |
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