Volcanic Ash Activates the NLRP3 Inflammasome in Murine and Human Macrophages

Volcanic ash is a heterogeneous mineral dust that is typically composed of a mixture of amorphous (glass) and crystalline (mineral) fragments. It commonly contains an abundance of the crystalline silica (SiO2) polymorph cristobalite. Inhalation of crystalline silica can induce inflammation by stimul...

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Үндсэн зохиолчид:	David E. Damby, Claire J. Horwell, Peter J. Baxter, Ulrich Kueppers, Max Schnurr, Donald B. Dingwell, Peter Duewell
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2018-01-01
Цуврал:	Frontiers in Immunology
Нөхцлүүд:	inflammasome NLRP3 reactive oxygen species lysosomal damage volcanic ash cristobalite
Онлайн хандалт:	http://journal.frontiersin.org/article/10.3389/fimmu.2017.02000/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!