ORMDL3/GSDMB genotype as a risk factor for early-onset adult asthma is linked to total serum IgE levels but not to allergic sensitization

Background: An orosomucoid-like 3 (ORMDL3)/gasdermin B (GSDMB) gene locus on chromosome 17q is consistently associated with childhood-onset asthma, which is highly atopic. As some evidence suggests the relationship between asthma and allergic sensitization reflects asthma patient susceptibility to a...

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Detaylı Bibliyografya
Asıl Yazarlar:	Haruna Kitazawa, Hironori Masuko, Jun Kanazawa, Rie Shigemasa, Kentaro Hyodo, Hideyasu Yamada, Yohei Yatagai, Yoshiko Kaneko, Hiroaki Iijima, Takashi Naito, Takefumi Saito, Emiko Noguchi, Satoshi Konno, Tomomitsu Hirota, Mayumi Tamari, Tohru Sakamoto, Nobuyuki Hizawa
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	Elsevier 2021-01-01
Seri Bilgileri:	Allergology International
Konular:	Asthma phenotype Early-onset asthma Genetics Immunoglobulin E (IgE) ORMDL3/GSDMB
Online Erişim:	http://www.sciencedirect.com/science/article/pii/S1323893020300599
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ORMDL3/GSDMB genotype as a risk factor for early-onset adult asthma is linked to total serum IgE levels but not to allergic sensitization

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