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The Niemann–Pick C1 Protein of Patients with Hepatocellular Carcinoma Is Associated with Survival Time in Males and Tumor Size in Females

<b>Background/Objectives:</b> The Niemann–Pick C1 (NPC1) protein regulates cellular cholesterol homeostasis, which is disrupted in hepatocellular carcinoma (HCC). Sex differences in cholesterol metabolism may also be related to NPC1 expression in HCC. A sex-specific analysis was, therefore, performe...

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Principais autores: Florian Weber, Katja Evert, Alexander Scheiter, Sophie von Sachsen-Coburg, Kirsten Utpatel, Christa Buechler
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2025-07-01
Serier:Biomedicines
Fag:
disease etiology
sex
UICC score
survival
Online adgang:https://www.mdpi.com/2227-9059/13/7/1707
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