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Reading the immune clock: a machine learning model predicts mouse immune age from cellular patterns

Abstract Aging is accompanied by profound alterations in the immune system; yet, an accurate prediction of immunological age remains challenging. While transcriptomic approaches have yielded insights into immune aging, protein-level profiling and machine learning-based prediction tools remain underd...

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Hauptverfasser: Hyun Bo Sim, Ji-Hun Jang, Seul-Ki Mun, Sonny C. Ramos, Dae-Han Park, Yu-Jeong Choi, Ji Yeon Han, Ju-Bin Lee, Ho Seok Chung, Kyung-Bok Lee, Dong-Jo Chang, Seung-Hyun Jeong, Jong-Jin Kim
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2025-12-01
Schriftenreihe:Nature Communications
Online-Zugang:https://doi.org/10.1038/s41467-025-67393-1
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