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In silico approaches for the identification of potential allergens among hypothetical proteins from Alternaria alternata and its functional annotation

Abstract Direct exposure to the fungal species Alternaria alternata is a major risk factor for the development of asthma, allergic rhinitis, and inflammation. As of November 23rd 2020, the NCBI protein database showed 11,227 proteins from A. alternata genome as hypothetical proteins (HPs). Allergens...

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Huvudupphov: Rajamanikandan Sundararaj, Amala Mathimaran, Dhamodharan Prabhu, Balajee Ramachandran, Jeyakanthan Jeyaraman, Saravanan Muthupandian, Tsehaye Asmelash
Materialtyp: Artigo
Språk:Inglês
Utgiven: Nature Portfolio 2024-03-01
Serie:Scientific Reports
Ämnen:
Alternaria alternata
AlgPred
SDAP
Structure–function relationship and drug discovery
Länkar:https://doi.org/10.1038/s41598-024-55463-1
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