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Cholesterol-25-hydroxylase Is a Chicken ISG That Restricts ALV-J Infection by Producing 25-hydroxycholesterol

The avian leukosis virus subgroup J (ALV-J) belongs to the chicken retrovirus that causes enormous economic losses in the poultry industry. Interferon-stimulated genes (ISGs) are critical for controlling virus infections. Here, we identified 897 type I ISGs induced by interferon-α (IFN-α)...

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Principais autores: Tingting Xie, Min Feng, Manman Dai, Guodong Mo, Zhuohao Ruan, Guiyan Wang, Meiqing Shi, Xiquan Zhang
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2019-05-01
Serier:Viruses
Fag:
chicken
ISG
ALV-J
<i>CH25H</i>
Online adgang:https://www.mdpi.com/1999-4915/11/6/498
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