Prevention of CMV/EBV reactivation by double-specific T cells in patients after allogeneic stem cell transplantation: results from the randomized phase I/IIa MULTIVIR-01 study

IntroductionAllogeneic stem cell transplantation is used to cure hematologic malignancies or deficiencies of the hematopoietic system. It is associated with severe immunodeficiency of the host early after transplant and therefore early reactivation of latent herpesviruses such as CMV and EBV within...

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Hauptverfasser:	Armin Gerbitz, Regina Gary, Michael Aigner, Andreas Moosmann, Anita Kremer, Christoph Schmid, Klaus Hirschbuehl, Eva Wagner, Beate Hauptrock, Daniel Teschner, Wolf Roesler, Bernd Spriewald, Johanna Tischer, Stephanie Moi, Heidi Balzer, Stefanie Schaffer, Judith Bausenwein, Anja Wagner, Franziska Schmidt, Jens Brestrich, Barbara Ullrich, Stefanie Maas, Susanne Herold, Julian Strobel, Robert Zimmermann, Volker Weisbach, Leo Hansmann, Fernanda Lammoglia-Cobo, Mats Remberger, Matthias Stelljes, Francis Ayuk, Robert Zeiser, Andreas Mackensen
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2023-10-01
Schriftenreihe:	Frontiers in Immunology
Schlagworte:	cytomegalovirus CMV Epstein-Barr virus EBV allogeneic stem cell transplantation (SCT) epitope specificity prevention
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1251593/full
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