A Patient‐Derived Organ‐on‐Chip Platform for Modeling the Tumor Microenvironment and Drug Responses in Pancreatic Cancer

ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) is a fatal malignancy. Current conventional chemotherapeutics are inadequate in controlling the disease; hence, there is an urgent need for precision medicine. Ex vivo models that replicate the tumor and its microenvironment can advance precision medi...

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Principais autores:	Darbaz Adnan, Natan Roberto deBarros, Luca S. Santovito, Xuhong Cheng, Kristi M. Lawrence, Mariah K. Barnett, Martine D. Boetto, Neal Mehta, Ajaypal Singh, Lin Cheng, Xiangsheng Huang, Faraz Bishehsari
Formato:	Artigo
Idioma:	Inglês
Publicado:	Wiley 2026-03-01
Series:	Advanced Science
Assuntos:	microfluidic organ on chip pancreatic cancer patient derived organoids tumor microenvironment
Acceso en liña:	https://doi.org/10.1002/advs.202508934
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