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Unconjugated bilirubin differentially affects the redox status of neuronal and astroglial cells

We investigated whether nerve cell damage by unconjugated bilirubin (UCB) is mediated by oxidative stress and ascertained the neuronal and astroglial susceptibility to injury. Several oxidative stress biomarkers and cell death were determined following incubation of neurons and astrocytes isolated f...

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Principais autores: Maria A. Brito, Alexandra I. Rosa, Ana S. Falcão, Adelaide Fernandes, Rui F.M. Silva, D. Allan Butterfield, Dora Brites
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2008-01-01
Serier:Neurobiology of Disease
Fag:
Astrocytes
Cell-type vulnerability
Cell death
Glutathione
Lipid peroxidation
Neurons
Online adgang:http://www.sciencedirect.com/science/article/pii/S096999610700174X
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