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A longitudinal evaluation of localised chronic Pseudomonas aeruginosa infection in cystic fibrosis rat models

Abstract Recurrent bacterial infections with Pseudomonas aeruginosa result in chronic airway inflammation, lung damage and eventual respiratory failure, and are the major cause of morbidity and mortality in people with cystic fibrosis (CF). Animal models are essential for understanding disease progr...

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Principais autores: Nicole Reyne, Bernadette Boog, Patricia Cmielewski, Alexandra McCarron, Ronan Smith, Nathan Rout-Pitt, Nina Eikelis, Kris Nilsen, John Finnie, Jennie Louise, David Parsons, Martin Donnelley
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2026-03-01
Serier:BMC Microbiology
Fag:
Pseudomonas aeruginosa
Lung infection
Cystic fibrosis
Animal model
Online adgang:https://doi.org/10.1186/s12866-026-04893-0
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