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Force-Induced Changes of PilY1 Drive Surface Sensing by Pseudomonas aeruginosa

ABSTRACT During biofilm formation, the opportunistic pathogen Pseudomonas aeruginosa uses its type IV pili (TFP) to sense a surface, eliciting increased second-messenger production and regulating target pathways required to adapt to a surface lifestyle. The mechanisms whereby TFP detect surface cont...

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Autors principals: Shanice S. Webster, Marion Mathelié-Guinlet, Andreia F. Verissimo, Daniel Schultz, Albertus Viljoen, Calvin K. Lee, William C. Schmidt, Gerard C. L. Wong, Yves F. Dufrêne, George A. O’Toole
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2022-02-01
Col·lecció:mBio
Matèries:
type 4 pili
force
PilY1
von Willebrand A domain
surface sensing
c-di-GMP
Accés en línia:https://journals.asm.org/doi/10.1128/mbio.03754-21
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