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Neurogenesis and Neuroinflammation in Dialogue: Mapping Gaps, Modulating Microglia, Rewiring Aging

<b>Background:</b> Aging brains are shaped by a persistent dialogue between declining neurogenesis and rising neuroinflammation. Neural stem cells progressively lose regenerative capacity, while microglia and astrocytes shift toward maladaptive states that erode synaptic plasticity and cognition. Th...

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Main Author: Masaru Tanaka
Format: Artigo
Language:Inglês
Published: MDPI AG 2026-01-01
Series:Cells
Subjects:
neurogenesis
neuroinflammation
aging brain
microglia
hippocampus
cognitive decline
Online Access:https://www.mdpi.com/2073-4409/15/1/78
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