Translational error in mice increases with ageing in an organ-dependent manner

Abstract The accuracy of protein synthesis and its relation to ageing has been of long-standing interest. To study whether spontaneous changes in the rate of ribosomal error occur as a function of age, we first determined that stop-codon readthrough is a more sensitive read-out of mistranslation due...

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Bibliografiske detaljer

Principais autores:	Erik C. Böttger, Harshitha Santhosh Kumar, Adrian Steiner, Emmanuel Sotirakis, Kader Thiam, Patricia Isnard Petit, Petra Seebeck, David P. Wolfer, Dimitri Shcherbakov, Rashid Akbergenov
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Portfolio 2025-02-01
Serier:	Nature Communications
Online adgang:	https://doi.org/10.1038/s41467-025-57203-z
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