Akt and mTOR in B cell activation and differentiation
Activation of phosphoinositide 3-kinase (PI3K) is required for B cell proliferation and survival. PI3K signaling also controls key aspects of B cell differentiation. Upon engagement of the B cell receptor (BCR), PI3K activation promotes Ca2+ mobilization and activation of NFκB-dependent transcriptio...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2012-08-01
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| Serie: | Frontiers in Immunology |
| Soggetti: | |
| Accesso online: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00228/full |
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