Improving the Methanol Tolerance of an Escherichia coli Methylotroph via Adaptive Laboratory Evolution Enhances Synthetic Methanol Utilization

There is great interest in developing synthetic methylotrophs that harbor methane and methanol utilization pathways in heterologous hosts such as Escherichia coli for industrial bioconversion of one-carbon compounds. While there are recent reports that describe the successful engineering of syntheti...

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Bibliografische Detailangaben

Hauptverfasser:	R. Kyle Bennett, Gwendolyn J. Gregory, Jacqueline E. Gonzalez, Jie Ren Gerald Har, Maciek R. Antoniewicz, Eleftherios T. Papoutsakis
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2021-02-01
Schriftenreihe:	Frontiers in Microbiology
Schlagworte:	synthetic methylotrophy methanol tolerance E. coli methanol methanol toxicity
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fmicb.2021.638426/full
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