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Delivery of Therapeutic RNA to the Bone Marrow in Multiple Myeloma Using CD38‐Targeted Lipid Nanoparticles

Abstract Multiple myeloma (MM) is a cancer of differentiated plasma cells that occurs in the bone marrow (BM). Despite the recent advancements in drug development, most patients with MM eventually relapse and the disease remains incurable. RNA therapy delivered via lipid nanoparticles (LNPs) has the...

Whakaahuatanga katoa

I tiakina i:
Ngā kaituhi matua: Dana Tarab‐Ravski, Inbal Hazan‐Halevy, Meir Goldsmith, Lior Stotsky‐Oterin, Dor Breier, Gonna Somu Naidu, Anjaiah Aitha, Yael Diesendruck, Brandon D. Ng, Hagit Barsheshet, Tamar Berger, Iuliana Vaxman, Pia Raanani, Dan Peer
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Wiley 2023-07-01
Rangatū:Advanced Science
Ngā marau:
BM niche
cancer
lipid nanoparticles
MM murine model
multiple myeloma
RNA therapy
Urunga tuihono:https://doi.org/10.1002/advs.202301377
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