Weighted Gene Co-expression Network Analysis Identifies FKBP11 as a Key Regulator in Acute Aortic Dissection through a NF-kB Dependent Pathway

Acute aortic dissection (AAD) is a life-threatening disease. Despite the higher risk of mortality, currently there are no effective therapies that can ameliorate AAD development or progression. Identification of meaningful clusters of co-expressed genes or representative biomarkers for AAD may help...

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Bibliografische Detailangaben

Hauptverfasser:	Tao Wang, Xingwei He, Xintian Liu, Yujian Liu, Wenjun Zhang, Qiang Huang, Wanjun Liu, Luyang Xiong, Rong Tan, Hongjie Wang, Hesong Zeng
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2017-12-01
Schriftenreihe:	Frontiers in Physiology
Schlagworte:	WGCNA FKBP11 NF-kB p65 subunit MMPs pro-inflammatory cytokines vascular inflammation
Online-Zugang:	http://journal.frontiersin.org/article/10.3389/fphys.2017.01010/full
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