Neuronal Plasticity and Signal Transduction in Nociceptive Neurons: Implications for the Initiation and Maintenance of Pathological Pain

Pathological pain, consisting of tissue injury-induced inflammatory and nerve injury-induced neuropathic pain, is an expression of neuronal plasticity. One component of this is that the afferent input generated by injury and intense noxious stimuli triggers an increased excitability of nociceptive n...

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Detalhes bibliográficos

Principais autores:	Ru-Rong Ji, Clifford J. Woolf
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2001-02-01
coleção:	Neurobiology of Disease
Assuntos:	pathological pain MAP kinase nociceptive neurons spinal cord primary sensory neurons central sensitization
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S0969996100903607
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