Barrier-free, open-top microfluidic chip for generating two distinct, interconnected 3D microvascular networks

Abstract Developing microphysiological cell culture platforms with a three-dimensional (3D) microenvironment has been a significant advancement from traditional monolayer cultures. Still, most of the current microphysiological platforms are limited in closed designs, i.e. are not accessible after 3D...

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Autores principales:	Alma Yrjänäinen, Elina Mesiä, Ella Lampela, Joose Kreutzer, Jorma Vihinen, Kaisa Tornberg, Hanna Vuorenpää, Susanna Miettinen, Pasi Kallio, Antti-Juhana Mäki
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Nature Portfolio 2024-10-01
Colección:	Scientific Reports
Materias:	Organ-on-Chip Microphysiological systems Vascularization Interstitial flow 3D cell culture
Acceso en línea:	https://doi.org/10.1038/s41598-024-74493-3
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