A robust workflow to benchmark deconvolution of multi-omic data
Abstract Background Tumour heterogeneity significantly affects cancer progression and therapeutic response, yet quantifying it from bulk molecular data remains challenging. Deconvolution algorithms, which estimate cell type proportions in bulk samples, offer a potential solution. However, there is n...
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| Autors principals: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BMC
2025-12-01
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| Col·lecció: | Genome Biology |
| Accés en línia: | https://doi.org/10.1186/s13059-025-03897-9 |
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