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Distinct Immunophenotypes of T Cells in Bronchoalveolar Lavage Fluid From Leukemia Patients With Immune Checkpoint Inhibitors-Related Pulmonary Complications

Patients with acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) treated with immune checkpoint inhibitors (ICIs) are at risk of pneumonitis as well as pneumonia (combined henceforth as ICI-related pulmonary complications). Little is known about the cellular and molecular mechanisms und...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Sang T. Kim, Ajay Sheshadri, Vickie Shannon, Dimitrios P. Kontoyiannis, Hagop Kantarjian, Guillermo Garcia-Manero, Farhad Ravandi, Jin S. Im, Prajwal Boddu, Lara Bashoura, Diwakar D. Balachandran, Scott E. Evans, Saadia Faiz, Wilfredo Ruiz Vazquez, Margarita Divenko, Rohit Mathur, Samantha P. Tippen, Curtis Gumbs, Sattva S. Neelapu, Aung Naing, Linghua Wang, Adi Diab, Andrew Futreal, Roza Nurieva, Naval Daver
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021-01-01
Schriftenreihe:Frontiers in Immunology
Schlagworte:
pneumonitis
Th17/Th1 cells
checkpoint inhibitor
acute myeloid leukemia
immune-related adverse event
Online-Zugang:https://www.frontiersin.org/articles/10.3389/fimmu.2020.590494/full
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