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Utilization of carbon catabolite repression for efficiently biotransformation of anthraquinone O-glucuronides by Streptomyces coeruleorubidus DM

Carbon catabolite repression (CCR) is a highly conserved mechanism that regulates carbon source utilization in Streptomyces. CCR has a negative impact on secondary metabolite fermentation, both in industrial and research settings. In this study, CCR was observed in the daunorubicin (DNR)-producing s...

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Huvudupphov: Chen Tao, Quyi Wang, Junyang Ji, Ziyue Zhou, Bingjie Yue, Ran Zhang, Shu Jiang, Tianjie Yuan
Materialtyp: Artigo
Språk:Inglês
Utgiven: Frontiers Media S.A. 2024-04-01
Serie:Frontiers in Microbiology
Ämnen:
anthraquinone
glucuronidation
Streptomyces
biotransformation
carbon catabolite repression
Länkar:https://www.frontiersin.org/articles/10.3389/fmicb.2024.1393073/full
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