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Lysophosphatidic acids are new substrates for the phosphatase domain of soluble epoxide hydrolase

Soluble epoxide hydrolase (sEH) is a bifunctional enzyme that has a C-terminus epoxide hydrolase domain and an N-terminus phosphatase domain. The endogenous substrates of epoxide hydrolase are known to be epoxyeicosatrienoic acids, but the endogenous substrates of the phosphatase activity are not we...

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Autori principali: Ami Oguro, Susumu Imaoka
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2012-03-01
Serie:Journal of Lipid Research
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Accesso online:http://www.sciencedirect.com/science/article/pii/S0022227520413653
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